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BioX-Lab · Biointerfaces

Why the interface decides: cell fate on nanostructured surfaces

The question sounds almost naive: why does the same alloy behave so differently once its surface is patterned at the nanoscale? Because cells never meet the bulk material — they meet its first few nanometres.

Eadh = γcell A ( 1 − cos θ )

Adhesion energy scales with effective contact area, and nanotopography rewrites that area completely.

M. Okafor — worth connecting this to the 2024 osseointegration data. Same mechanism?

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Eadh = γcell A ( 1 − cos θ )
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cells meet its first few nanometres — not the bulk.
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In the press
Quanta MagazineThe surface that decides a cell's fate2024
Nature NewsWhy nanotopography rewrites adhesion2023
El País · MateriaLa ciencia que escucha a las células2022
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